And it increasingly appears that the disease can change the brain in different ways. "We are just scratching the surface," he said. From the first cases in central China to vaccinations being rolled out a year later, here are a dozen key developments in the spread and subsequent fight against COVID-19. You can manage them any time by clicking on the notification icon. "It occurred naturally and it had to have been many months earlier, perhaps a year, perhaps more than a year.". January 11 marks the anniversary of China confirming its first death from COVID-19, a 61-year-old man who was a regular at the now-notorious Wuhan wet market. The trail has now gone cold, with the drip of subsequent clues only adding to the confusion, including findings that the virus may have existed in Europe and Brazil before Wuhan's outbreak, unconfirmed suggestions which China has seized upon to deflect blame. Dr. Juliette Madrigal has seen a fair number of patients in recent months suffering from anxiety while ill with COVID-19. A BEHIND-the-scenes look at a Bradford hospital’s Covid ward has been showcased on national TV. 'I DO' When Kerr, 31, and O'Brien, 36, arrived at the hospital, both needed a CPAP machine to breathe. On April 2, more than 3.9 billion people - half of the world's population - are forced or called on to confine themselves, according to an AFP count. Hospital staff have noticed a … "(The species) actually doesn't matter. This occurs when an infection causes the body's immune system to flood the bloodstream with inflammatory proteins known as cytokines. Augmenting the doubt, in December China said the number of coronavirus cases circulating in Wuhan may have been 10 times higher early in the epidemic than revealed by official figures at the time. Tayside health chiefs are dealing with a coronavirus outbreak in a surgical ward at Dundee’s Ninewells Hospital. The pandemic also picks up pace in the US, where its handling is a key issue in the presidential campaign. That's because it may take months or even years for a virus to develop the necessary mutations to become highly contagious among humans. The unemployment rate in South Dakota has dropped to a level lower than before the coronavirus pandemic began. Beijing may want to hide regulatory or investigative lapses to avoid domestic embarrassment or global "blowback", said Daniel Lucey, a Georgetown University epidemiologist who closely tracks global outbreaks. Brazil becomes the country with the second biggest death toll after the US. Health and Human Services secretary nominee Xavier Becerra avoided giving a direct answer on what the Biden administration's timeline for developing a more robust vaccine distribution plan will look like. Then COVID-19 struck. Increasing research suggests that COVID-19 causes strokes by creating a "cytokine storm." He and his fellow researchers used brain organoids, which are brain tissues created from human stem cells. Indeed, scientists are just beginning to unravel how COVID-19 affects the brain. She says the overarching threat has already been exposed: a global wildlife trade that fosters a "combustible mix" of trafficked species, a known breeding ground for disease outbreaks. And it has kept foreign experts at arm's length, with a planned mission by World Health Organization virus sleuths now in limbo after China denied them entry. Synapses are the parts of the brain that enable nerve cells to pass electrical or chemical signals to each other. But if the virus invades the brain, then antiviral drugs, such as Remdesivir or Sofosbuvir, might prove more effective. "We had to wait a few days for our first kiss," Kerr told Reuters. Scientists aren't yet sure what causes the loss of smell. Experts say authorities may have destroyed or scrubbed away crucial evidence in a panicked initial response. All rights reserved. Northern Italy is locked down, quickly followed by the rest of the country. "This observation is so important because it reveals a potential mechanism to explain the neurological symptoms in COVID-19 patients," Muotri said. Still, the virus would likely have to invade the brain to cause other neurological problems, such as psychosis, dementia, or anxiety. Muotri's research also found that Sofosbuvir, an antiviral drug approved by the Food and Drug Administration, was able to stop the virus from replicating in the brain. But the trail ends there, clouded by a mishmash of subsequent clues that suggest its origins may predate Wuhan as well as conspiracy theories - amplified by US President Donald Trump - that it leaked from a Wuhan lab. If strokes and intracerebral hemorrhages are due to inflammation caused by the immune system's response to COVID-19, then anti-inflammatory drugs are a likely treatment. British couple Elizabeth Kerr and Simon O'Brien had been planning to marry in June. Britain is the first Western nation to start vaccinating, with rollout in the rest of Europe uneven, causing widespread frustration. The 27-nation European Union closes its external borders. Diana Bell, a wildlife disease expert at the University of East Anglia who has studied the SARS virus, Ebola and other pathogens, said focusing on a particular origin species is misguided. We don't need to know the source, we just need to stop that sodding mixing of animals in markets," she said. © Al Nisr Publishing LLC 2021. The Wuhan market might not even be the issue, Lucey adds. Associated Press | Jan 01, 2021 at 5:15 PM . On February 15, France reports the first death confirmed outside Asia, a Chinese tourist. On April 29, the battered US aircraft manufacturer Boeing slashes 16,000 jobs. By March 6, more than 100,000 cases have been recorded around the world. The same day the threshold of one million cases is crossed. Then COVID-19 struck. "In some ways, they were quite open, in others they were less than open.". Sick couple rushed to marry in UK COVID ward now have second chance. While it seems reasonable that people with a potentially life-threatening disease would get anxious, Madrigal is increasingly convinced that the anxiety is a side effect that the coronavirus has on the brain. It's chaotic and dysfunctional," said Daszak. 24/01/2021. COVID-19: Sick couple have 'only chance' wedding at a coronavirus hospital ward in UK. The surge of cases and deaths in Latin America causes concern. We’ll send you latest news updates through the day. The National Park Service announced on Saturday that the Washington Monument and several other indoor areas on the National Mall will remain closed in order to mitigate the spread of the coronavirus pandemic. Unfortunately, the new administration has missed a key opportunity to accomplish both goals by choosing to extend rather than end the Centers for Disease Control and Prevention’s eviction moratorium. Perhaps most importantly, they found that 48 hours after infection, the virus reduced the number of synapses in the brain cells by about 50%. COVID-19: A year after first death in China, coronavirus source still a puzzle. There is little dispute that the virus which brought the world to its knees sparked its first known outbreak in late 2019 at a wet market in the central Chinese city of Wuhan where wildlife was sold as food, and the pathogen is believed to have originated in an undetermined bat species. "We've also seen quite a few patients complain of what we now call 'COVID Brain,'" she said. But China has since failed to publicly connect any dots, releasing scant information on animal and environmental samples taken at the market that could aid investigators, experts say. In October, infections start to spiral in Europe, where many countries order new lockdowns and curfews. Many studies have found elevated levels of a clot-dissolving protein called a "D-dimer" in patients with COVID-19 who have experienced strokes. On January 7, the WHO calls the surging cases and new variants "alarming... and a tipping-point in the course of the pandemic.". The Chicago Teachers Union "overwhelmingly" voted to remain working from home due to concerns over the coronavirus, which defies the Chicago Public Schools’ reopening plans. British couple Elizabeth Kerr and Simon O'Brien had been planning to marry in June. Register to read and get full access to gulfnews.com, By clicking below to sign up, you're agreeing to our Majority Leader Chuck Schumer criticized Minority Leader Mitch McConnell on Sunday for stalling power-sharing negotiations as the Senate prepares to address the "three essential items on our plate" — impeachment, coronavirus relief, and confirming Cabinet members. British Airways pilot Nicholas Synnott, 59, spent 243 days on a Covid ward in UT Health and Memorial Hermann Hospital in Houston, Texas. Nearly two million deaths later, the pandemic is out of control across much of the world, leaving tens of millions ill, a pulverised global economy and recriminations flying between nations. It was confirmed on Sunday a “small number” of cases linked to Ward … Terms of Use That would mean that the coronavirus doesn't have to invade the brain to cause a stroke. He notes that the virus was already spreading rapidly in Wuhan by December 2019, indicating that it was in circulation much earlier. Establishing the source is vital for extinguishing future outbreaks early, leading virologists say, providing clues that can guide policy decisions on whether to cull animal populations, quarantine affected persons, or limit wildlife hunting and other human-animal interactions. Indeed, a recent article in the British Medical Journal did not find the virus in the cerebrospinal fluid of two patients who experienced both COVID-19 and a stroke. A recent study published in the Lancet found that of 125 people who had COVID-19 and were diagnosed with a neurological problem, 57 had suffered a stroke, and 10 had suffered psychosis. Daszak remains hopeful the source can be found, especially after US President Donald Trump's re-election loss. Yet Muotri warns that scientists may be a long way from solving this puzzle. 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